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| Name | Role |
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| Vincent Cassel | Otto Gross |
| Sarah Gadon | Emma Jung |
| Andre Hennicke | Professor Eugen Bleuler |
| Arndt Schwering-Sohnrey | Sandor Ferenczi |
| Mignon Reme | Jung's Secretary |
| Mareike Carriere | Food Nurse |
| Franziska Arndt | Bath Nurse |
| Wladimir Matuchin | Nikolai Spielrein |
| Andre Dietz | Medical Policeman |
| Anna Thalbach | Bathtub Patient |
| Sarah Marecek | Orchard Nurse |
| Bjorn Geske | Orderly |
| Markus Haase | Orderly |
| Christian Serritiello | Ship's Officer |
| Clemens Giebel | Ship's Steward |
| Theo Meller | Karl Abraham |
| Jost Grix | Leonhard Seif |
| Severin von Hoensbroech | Johan van Ophuijsen |
| Torsten Knippertz | Ernest Jones |
| Dirk S. Greis | Franz Riklin |
| Katharina Palm | Martha Freud |
| Nina Azizi | Minna Bernays |
| Julie Chevallier | Anna Freud |
| Cynthia Cosima | Sophie Freud |
| Mirko Naeger-Guckeisen | Ernst Freud |
| Julia Mack | Mathilde Freud |
| Andrea Magro | Jean Freud |
| Aaron Keller | Oliver Freud |
| Nadine Salomon | Maid at Freud's House |
| Naike Jaszczyk | Agathe Jung |
| Sarah Adams | Gret Jung |